2022年3月3日，在这春暖花开的日子，2020年度广州市医学会优秀论文复评会在广州隆重召开。复评专家委员会由共和国勋章获得者、中国工程院院士、广州市医学会会长钟南山、副会长、秘书长及各专科分会主任委员等93位专家组成，学会监事长列席本次会议。会议严格按照疫情防控要求执行。本次会议由广州市医学会会长钟南山院士主持。

钟南山主持会议

论文评选情况

2020年度

2020年度优秀论文评选共收到27个会员单位选送参评论文690篇，符合评选要求篇数为600篇，涵盖76个医学专业。经76个专科分会的专家初评，303篇论文入选优秀论文复评。

优秀论文复评会议现场

一等奖候选论文作者答辩风采

在会长钟南山院士的主持下，复评会对初评推荐一、二等奖的60篇论文进行复评。16位初评为一等奖论文的作者现场进行介绍和答辩，44篇初评为二等奖论文由推荐的专科分会主任委员进行论文介绍和答疑。最后由93位评委对60篇论文采用无记名现场扫码投票，评选出一等奖论文10篇，二等奖论文36篇。

主委介绍初评二等奖论文风采

评委风采

最后，会长钟南山院士表示，广州市医学会优秀论文评选活动开展已将近40年，见证了医学学术水平逐步提高，近几年征集的优秀论文中多了很多临床研究型论文。希望今后评选优秀论文应向临床的文章聚焦，把握推荐获奖的临床和基础论文比例,对临床的论文进入一等奖和二等奖要适应倾斜。会长钟院士强调，优秀论文评选活动是广州市医学会鼓励全体会员勇于创新，勇于发现问题，运用问题导向思维，从文献中发现问题，将临床和科研教学成果综合成文，最后回归到文献。

一直以来，广州市医学会致力举办的医学优秀论文评选活动为提高广州市的医学科学水平，推动卫生事业的发展发挥了积极的作用。

合影照片

一等奖获奖名单

序号评审专科论文题目
1呼吸病学分会Clinical acteristics of Coronavirus Disease 2019 in China中国新型冠状病毒2019的临床特征
2呼吸病学分会Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, Treatment新冠肺炎非转基因小鼠模型的构建，用于新冠致病机制、疫苗、治疗等研究
3血液学分会Reduced Platelet miR-223 Induction in Kawasaki Disease Leads To Severe Coronary Artery Pathology Through a miR-223/PDGFRβ Vascular Smooth Muscle Cell Axis血小板miR-223降低参与川崎病冠脉损伤形成:诊断和治疗策略
4感染病学分会Temporal dynamics in viral shedding transmissibility of COVID-19新冠病毒的排毒与传播能力的时间动态变化
5儿科学分会Characteristics of pediatric SARS-CoV-2 infection potential evidence for persistent fecal viral shedding小儿 SARS-CoV-2 感染的特征和持续粪便病毒脱落的潜在证据
6病理学分会An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 tumorigenesis             一种癌多肽调节了m6A读取器IGF2BP1对m6A的识别和肿瘤的发生发展
7精神病学分会Chronic administration of ketamine induces cognitive deterioration by restraining synaptic signaling长期服用氯胺酮通过抑制突触信号传递而导致认知功能恶化
8生殖医学分会Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells.使用3D打印的植入缺氧诱导因子（HIF-1α）突变干细胞的水凝胶支架对受损海绵体进行功能重建
9感染病学分会A compromised specifific humoral immune response against the SARS-CoV-2 receptor-binding domain is related to viral persistence periodic shedding in the gastrointestinal tract针对新型冠状病毒受体结合域的受损特异性体液免疫应答与胃肠道中的病毒持久性和周期性脱落有关
10介入放射学分会Nanodrug with ROS pH Dual-Sensitivity Ameliorates Liver Fibrosis via Multicellular RegulationROS和pH双敏感的纳米药物通过多细胞调控改善肝纤维化

二等奖获奖名单

序号评审专科论文题目
1心血管病学分会A self-doping conductive polymer hydrogel that can restore electrical impulse propagation at myocardial infarct to prevent cardiac arrhythmia preserve ventricular  function具有自掺杂作用的导电高分子水凝胶通过重建心肌梗死后纤维组织中的电脉冲传播进而预防心律失常和保护心室功能
2消化内镜学分会Prodigiosin impairs autophagosome-lysosome fusion that sensitizes colorectal cancer cells to 5-fluorouracil-induced cell deathProdigiosin 抑制自噬增强结直肠肿瘤对5-FU 敏感性的机制研究
3放射学分会Redox-responsive nanoparticles from disulfide bond-linked poly-(N-ε-carbobenzyloxy-L-lysine)-grafted hyaluronan copolymers as theranostic nanoparticles for tumor-targeted MRI chemotherapy基于透明质酸/聚N-ε-苄氧羰基-L-赖氨酸酯接枝聚合物的还原响应性纳米粒子构建的肿瘤靶诊疗一体化纳米探针
4检验医学分会Background-Free omatographic Detection of Sepsis Biomarker in Clinical Human Serum through Near-Infrared to Near-Infrared Upconversion Immunolabeling利用上转换近红外发光实现脓毒血症指标降钙素原无背景层析检测
5医院药学分会LncRNA HOTAIR-mediated MTHFR methylation inhibits 5-fluorouracil sensitivity in esophageal cancer cells长链非编码RNA HOTAIR通过促进MTHFR基因启动子甲基化促进食管癌的发生并抑制5-FU化疗的敏感性
6神经内科学分会Optimization of in silico tools for predicting genetic variants: individualizing for genes with molecular sub-regional stratification遗传变异预测的新型优化模型：基于亚分子的基因个体化分析
7精准分子诊断学分会Screening Therapeutic Agents Specific to Breast Cancer Stem Cells Using a Microfluidic Single-Cell Clone-Forming Inhibition Assay微流控芯片单细胞克隆形成试验用于乳腺癌干细胞靶向药物筛选
8心血管病学分会M1-like macrophage-derived exosomes suppress angiogenesis exacerbate cardiac dysfunction in a myocardial infarction microenvironmentM1型巨噬细胞来源的外泌体抑制心肌梗死微环境中的血管生成并加剧心脏功能障碍
9呼吸病学分会Longitudinal hematologic immunologic variations associated with the progression of COVID-19 patients in China与中国COVID-19患者进展相关的纵向血液学和免疫学变化
10肝病学分会LRPPRC sustains Yap-P27-mediated cell ploidy P62-HDAC6-mediated autophagy maturation suppresses genome instability hepatocellular carcinomasLRPPRC 维持 Yap-P27 介导的细胞倍性和 P62-HDAC6 介导的自噬成熟并抑制基因组不稳定性和肝细胞癌
11神经内科学分会CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes多巴胺神经元 CNTNAP4 基因缺陷诱发帕金森病表型
12神经外科学分会Exosomes derived from human neural stem cells stimulated by interferon gamma improve therapeutic ability in ischemic stroke modelγ-干扰素刺激前后神经干细胞分泌的外泌体在脑缺血中的治疗作用及机制
13胃肠外科学分会Small Protein Hidden in lncRNA LOC90024 Promotes“Cancerous”RNA Splicing Tumorigenesis隐藏在 lncRNALOC90024 中的小蛋白促进“癌性”RNA 剪接和肿瘤发生发展
14乳腺病学分会SRGN crosstalks with YAP to maintain chemoresistance stemness in breast cancer cells by modulating HDAC2 expressionSRGN-YAP相互对话可通过增强HDAC2的表达维持乳腺癌干细胞特性促进化疗抵抗
15超声医学分会Thermal Ablation Induces Transitory Metastatic Growth by Means of the STAT3 / c-Met Molecular Pathway in an Intrahepatic Colorectal Cancer Mouse Model射频消融通过STAT3/c-Met信号通路短暂诱导小鼠肝内转移瘤生长
16疼痛学分会Oxaliplatin-induced neuropathic pain involves HOXA6 via a TET1-dependent demethylation of the SOX10 promoter依赖于TET1的SOX10启动子区去甲基化调控HOXA6表达介导奥沙利铂引起的神经病理性疼痛
17妇产科学分会T-cadherin inhibits invasion migration of endometrial stromal cells in endometriosisT-钙粘蛋白抑制子宫内膜异位症患者子宫内膜间质细胞的侵袭和迁移
18泌尿外科学分会GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-PhosphateGPD1 通过协同增加细胞内总三磷酸甘油来增强二甲双胍的抗癌作用
19血液肿瘤学分会Anti-bacterial anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 c-Maf抗菌和抗病毒药物南昌霉素通过靶向Otub1和c-Maf而抗多发性骨髓瘤的研究
20呼吸病学分会Clinical application of an intelligent oropharyngeal swab robot:implication for the COVID-19 pandemic智能咽拭子机器人在新型冠状病毒大流行中应用的启示
21肿瘤学分会Evaluation of Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Stage III Epithelial Ovarian CancerⅢ期上皮性卵巢癌肿瘤细胞减灭术加或不加腹腔热灌注化疗的疗效评价
22康复医学分会TMS brain mapping of the pharyngeal cortical representation in healthy subjects单脉冲TMS 绘制健康人咽部肌群皮质代表区
23感染病学分会Kinetics of viral load antibody response in relation to_COVID-19 severity新冠肺炎患者疾病严重程度与病毒载量、抗体反应动态变化相关性研究
24精神病学分会Inflammation, brain structure cognition interrelations among individuals with differential risks for bipolar disorder炎症、脑结构和认知功能三者在具有不同双相障碍患病风险个体中的相互关系
25皮肤病学分会Spinal GRPR NPRA Contribute to onic Itch in a Murine Model of Allergic Contact Dermatitis脊髓GRPR和NPRA 参与过敏性接触性皮炎小鼠模型的慢性痒
26肿瘤学分会A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties therapeutic targets肝细胞分化模型揭示了两个不同癌基因的肝癌亚型特性和治疗靶标
27微创泌尿外科学分会Management of large renal stones with super-mini percutaneous nephrolithotomy: an international multicentre comparative study超微型经皮肾镜取石术（SMP）治疗大肾结石：一项国际多中心比较研究
28感染病学分会Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity血液中检测到2019-nCoV病毒RNA是临床症状更严重的有力指标
29放射学分会Theranostic Nanoparticles with Aggregation-Induced Emission MRI Contrast Enhancement acteristics as a Dual-Modal Imaging Platform for Image-Guided Tumor Photodynamic Therapy具有聚集诱导发光和MRI 对比度增强特性的双模态成像纳米粒子介导肿瘤光动力治疗
30全科医学分会Associations between residential greenness blood lipids in Chinese Uyghur adults维吾尔族成年人居住环境绿地水平与血脂的关系研究
31胸心外科学分会Comprehensive analysis of differential immunocyte infiltration the potential ceRNA networks during epicardial adipose tissue development in congenital heart disease先天性心脏病心外膜脂肪发育相关免疫微环境及内源竞争性RNA网络谱图构建
32中青年医学学术研究会miR-301a Suppression within Fibroblasts Limits the Progression of Fibrosis through the TSC1/mTOR Pathway靶向成纤维细胞miR-301a抑制TSC1/mTOR通路限制肺纤维化的进展
33呼吸病学分会Arnold Nerve Reflex: Vagal Hypersensitivity in onic Cough with Various Causes阿诺德神经反射各种原因慢性咳嗽的迷走神经超敏反应
34检验医学分会Systematic analysis of gut microbiota in pregnant women its correlations with individual heterogeneity孕妇肠道菌群系统分析及其与个体异质性的相关性研究
35临床病态营养学分会High-Fat Diet Affects Heavy Metal Accumulation Toxicity to Mice Liver Kidney Probably via Gut Microbiota高脂饮食可能通过肠道菌群影响重金属在小鼠肝脏和肾脏中的积累和毒性
36骨科学分会Fibrochondrogenic differentiation potential of tendon-derived stem/progenitor cells from human patellar tendon人髌腱干细胞的纤维软骨分化潜力

来源：广州市医学会

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