科创中国
一种增强TRPV4-KCa2.3复合体耦联度的化合物及其在抗高血压中的应用
发布时间: 2022-03-31
基本信息
合作方式：
技术转让
成果类型：
发明专利
行业领域：
其他
成果介绍
METHOD OF PRODUCING A COMPOUND FOR ENHANCING THE COHESIVENESS OF THE COMPLEX SUBSTANCE ***
FIELD: ***: invention relates to a method of producing a compound of formula (1). Method is carried out by reacting propane diamine with tert-butoxycarbonyl in dichloromethane at temperature from 0 to 25 °C, ***, the protective amine is removed from the protective tert-***, the obtained amine derivative undergoes amino-ether exchange with 4-quinazolone-2-carboxylic acid ester to form the desired compound of formula (1).(1).EFFECT: method of producing a compound of formula (1), which strengthens the degree of cohesiveness of the complex substance *** cl, 5 dwg, 1 tbl⊙
成果亮点
团队介绍
成果资料
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